1.
Sci Rep
; 12(1): 10194, 2022 06 17.
Article
in English
| MEDLINE | ID: covidwho-1984424
ABSTRACT
Since the start of SARS-CoV-2 pandemic, children aged ≤ 12 years have always been defined as underrepresented in terms of SARS-CoV-2 infections' frequency and severity. By correlating SARS-CoV-2 transmission dynamics with clinical and virological features in 612 SARS-CoV-2 positive patients aged ≤ 12 years, we demonstrated a sizeable circulation of different SARS-CoV-2 lineages over the four pandemic waves in paediatric population, sustained by local transmission chains. Age < 5 years, highest viral load, gamma and delta clades positively influence this local transmission. No correlations between COVID-19 manifestations and lineages or transmission chains are seen, except for a negative correlation between B.1.1.7 and hospitalization.
Subject(s)
COVID-19 , SARS-CoV-2 , COVID-19/epidemiology , Child , Humans , Pandemics , SARS-CoV-2/genetics , Viral Load
2.
Sci Rep
; 12(1): 12814, 2022 Jul 27.
Article
in English
| MEDLINE | ID: covidwho-1960503